Comparison of aerosol delivery across combinations of drug delivery interfaces with and without concurrent high-flow nasal therapy
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چکیده
منابع مشابه
In vitro comparison of heliox and oxygen in aerosol delivery using pediatric high flow nasal cannula.
Drug administration via high flow nasal cannula (HFNC) has been described in pediatrics but the amount of albuterol delivery with an HFNC is not known. The purpose of this study is to quantify aerosol delivery with heliox and oxygen (O(2)) in a model of pediatric ventilation. A vibrating mesh nebulizer (Aeroneb Solo, Aerogen) was placed on the inspiratory inlet of a heated humidifier and heated...
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INTRODUCTION Use of submicrometer particles combined with condensational growth techniques has been proposed to reduce drug losses within components of high-flow nasal cannula therapy systems and to enhance the dose reaching the lower respiratory tract. These methods have been evaluated using continuous inhalation flow rather than realistic inhalation/exhalation breathing cycles. The goal of th...
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15 صفحه اولEffects of Tumour-induced Flow Patterns on Aerosol Drug Delivery
This manuscript presents a theoretical study of fluid dynamics in diseased lungs. The objective was to describe fluid behavior and assist in the development of new techniques for targeted delivery of drugs. Numerical simulations were conducted using FIDAP on the Cray T90 supercomputer. Two lung bifurcations with tumors in tracheobronchial airways were considered. Weibel [1] lung morphology and ...
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ژورنال
عنوان ژورنال: Intensive Care Medicine Experimental
سال: 2019
ISSN: 2197-425X
DOI: 10.1186/s40635-019-0245-2